(+-)-3-Quinuclidinol → HCID 54102030, compound

HRID 1005330Notes

Reaction equation

HRID 1005330 reaction equation
[C:1]1([N:11]=[C:12]=[O:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[N:14]12[CH2:21][CH2:20][CH:17]([CH2:18][CH2:19]1)[CH:16]([OH:22])[CH2:15]2>>[N:14]12[CH2:21][CH2:20][CH:17]([CH2:18][CH2:19]1)[CH:16]([O:22][C:12](=[O:13])[NH:11][C:1]1[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=[CH:3][CH:2]=1)[CH2:15]2

Participants

3

Reactant 2

HCID 15381(+-)-3-QuinuclidinolHCID 66589alpha-Naphthyl isocyanate

Product 1

HCID 54102030HCID 54102030, compound

Procedure

1-Naphthylisocyanate and 3-quinuclidinol were used. The title compound was isolated as a white solid (34%): mp 186-188° C.; FAB LRMS m /z 297 (MH+).

Sources & evidence

ORD record
ord-28ab1f78afd6442898524ecea4e16935
Source dataset
uspto-grants-2000_04
Patent number
US06054464

Reaction notes

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