Triethylamine → HCID 178510733, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of cis-2-methoxycarbonyl-2-(3-methoxycarbonylcyclobutyl)-3-(9-anthracenyl)propanoic acid (0.15 g, 0.36 mmol), dry triethylamine (37 mg, 0.37 mmol) and diphenylphosphonic azide (103 mg, 0.37 mmol) in dry toluene (5 ml) was heated with stirring at 100° C. under a nitrogen atmosphere for 5 hours. Work up and chromatography eluting with hexane-diethyl ether (17:8) as described in Example 16 (v) gave the title compound as a white solid.

Provenance & Evidence