Triethylamine → HCID 178510905, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of cis-2-methoxycarbonyl-2-(3-methoxy carbonylcyclobutyl)-4-(10,10-dioxido-9-thioxanthyl)butanoic acid (0.87 g, 1.79 mmol), triethylamine (0.19 g, 1.88 mmol) and diphenyl phosphonic azide (0.33 g, 1.88 mmol) in toluene (30 ml) were heated at 75° C. and worked up following the procedure described in Example 17(iii). The crude product was purified by chromatography on flash silica eluting with diethyl ether-hexane (7:3) to give a colourless oil and then crystallised from diethyl ether to give the title compound.

Provenance & Evidence