Palmitoyl chloride → HCID 136341911, compound

HRID 1005368Notes

Reaction equation

HRID 1005368 reaction equation
[C:1]([C@@:18]1([N:26]2[C:36]3[N:35]=[C:33]([NH2:34])[NH:32][C:30](=[O:31])[C:29]=3[N:28]=[CH:27]2)[O:25][C@H:22]([CH2:23][OH:24])[C@@H:20]([OH:21])[CH2:19]1)(=[O:17])[CH2:2][CH2:3][CH2:4]CCCCCCCCCCCC.C(Cl)(=O)CCC.C(Cl)(=O)CCCCCCCCCCCCCCC>>[C:1]([C@@:18]1([N:26]2[C:36]3[N:35]=[C:33]([NH2:34])[NH:32][C:30](=[O:31])[C:29]=3[N:28]=[CH:27]2)[O:25][C@H:22]([CH2:23][OH:24])[C@@H:20]([OH:21])[CH2:19]1)(=[O:17])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 3

HCID 8206Palmitoyl chlorideHCID 8855Butyryl chlorideHCID 136333583HCID 136333583, compound

Product 1

HCID 136341911HCID 136341911, compound

Procedure

This compound was prepared using the procedure for palmitoyl-2'-deoxyguanosine, substituting the appropriate amount of butyryl chloride for palmitoyl chloride, and isolating as follows: evaporating the solvent after 72 hours, triturating the resulting material in 1:1 diethyl ether-ethyl acetate, and recovering the product by filtration.

Workup

  1. customThis compound was prepared
  2. customisolating
  3. customevaporating the solvent after 72 hours
  4. customtriturating the resulting material in 1:1 diethyl ether-ethyl acetate
  5. customrecovering the product
  6. filtrationby filtration

Sources & evidence

ORD record
ord-b9862e1aa70848fc931ed667f8702093
Source dataset
uspto-grants-2000_04
Patent number
US06054441

Reaction notes

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