HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dibutoxycyclohexane → 2-[(1-Butoxycyclohexyloxy)methyl]-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dibutoxycyclohexane | HCID 243718 | — |
| Reactant | (5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol | HCID 473916 | — |
| Product | 2-[(1-Butoxycyclohexyloxy)methyl]-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole | HCID 18792012 | 30.9% |
Reaction Steps
The compound 14 (3.1 mg, 0.1 mmol) was converted to the acetal with 1,1-dibutoxycyclohexane (228 mg, 1 mmol) in the same manner as the example 14 to give the compound 16 (15 mg, 30%) as oil. Rf 0.44 (Al2O3 60, Type E, toluene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-b2ab2a707f264b7a858f4e433d52e597 |
| Source note | uspto-grants-2000_04 |