HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol → 2-(Cycloocten-1-yloxy)methyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol | HCID 473916 | — |
| Reactant | 1-Methoxycyclooct-1-ene | HCID 42586710 | — |
| Product | 2-(Cycloocten-1-yloxy)methyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole | HCID 54343979 | 25% |
Reaction Steps
The compound 14 (33.1 mg, 0.1 mmol) was converted to the enolether with 1-methoxycyclooctene (140 mg, 1 mmol) in the same manner as the example 16 to give the compound 18 (11.0 mg, 22%) as oil. Rf 0.50 (Al2O3 60, Type E, toluene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-2c0d051bbe284a18a74110cc6ffb3853 |
| Source note | uspto-grants-2000_04 |