1,1-Dibutoxycyclohexane → HCID 18792005, compound

HRID 1005532Notes

Reaction equation

HRID 1005532 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9][C:10]2[N:14]([CH3:15])[C:13]([CH2:16][CH2:17][OH:18])=[N:12][C:11]=2[CH:19]([CH3:21])[CH3:20])[CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH2:22]([O:26][C:27]1(OCCCC)[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1)[CH2:23][CH2:24][CH3:25]>>[Cl:8][C:6]1[CH:5]=[C:4]([S:9][C:10]2[N:14]([CH3:15])[C:13]([CH2:16][CH2:17][O:18][C:27]3([O:26][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]3)=[N:12][C:11]=2[CH:19]([CH3:21])[CH3:20])[CH:3]=[C:2]([Cl:1])[CH:7]=1

Participants

3

Reactant 2

HCID 2437181,1-DibutoxycyclohexaneHCID 4740102-(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)ethanol

Product 1

HCID 18792005HCID 18792005, compoundYield 29%

Procedure

The compound 22 (345 mg, 1 mmol) was converted to the acetal with 1,1-di-n-butoxycyclohexane (2.28 g, 00 mmol) in the same manner as the example 20 to give the compound 34 (145 mg, 29%).

Sources & evidence

ORD record
ord-f4e96c151fa44a3bb61783d066c152ca
Source dataset
uspto-grants-2000_04
Patent number
US06054591

Reaction notes

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