2-(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)ethanol → HCID 18792041, compound

HRID 1005534Notes

Reaction equation

HRID 1005534 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9][C:10]2[N:14]([CH3:15])[C:13]([CH2:16][CH2:17][OH:18])=[N:12][C:11]=2[CH:19]([CH3:21])[CH3:20])[CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH2:22]([O:28][C:29]1(OCCCCCC)[CH2:33][CH2:32][CH2:31][CH2:30]1)[CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>>[Cl:8][C:6]1[CH:5]=[C:4]([S:9][C:10]2[N:14]([CH3:15])[C:13]([CH2:16][CH2:17][O:18][C:29]3([O:28][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:33][CH2:32][CH2:31][CH2:30]3)=[N:12][C:11]=2[CH:19]([CH3:21])[CH3:20])[CH:3]=[C:2]([Cl:1])[CH:7]=1

Participants

3

Reactant 2

HCID 4740102-(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)ethanolHCID 18792002HCID 18792002, compound

Product 1

HCID 18792041HCID 18792041, compoundYield 34.7%

Procedure

The compound 22 (345 mg, 1 mmol) was converted to the acetal with 1,1-di-n-hexoxycyclopentane (2.72 g, 10 mmol) in the same manner as the example 20 to give the compound 36 (178 mg, 34.6%).

Sources & evidence

ORD record
ord-54e78e5b0833421caae4b295c06f278a
Source dataset
uspto-grants-2000_04
Patent number
US06054591

Reaction notes

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