HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 60108780, compound → HCID 60108785, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 60108780 | HCID 60108780 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 60108785 | HCID 60108785 | 77.5% |
Reaction Steps
To a solution of 4-(1H-indol-7-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester (100 mg) in EtOH (20 mL) was added 10% Pd/C (20 mg). The reaction was placed on a Parr shaker at 55 psi H2 for 24 h. The reaction was filtered through Celite™ and concentrated to afford 4-(1H-indol-7-yl)-piperidine-1-carboxylic acid tert-butyl ester (22) as a clear oil (78 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787535B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-52d04bef45344eb5a04475b15473f9a6 |
| Source note | uspto-grants-2004_09 |