Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005658Generated: October 29, 2026

HCID 60108780, compound → HCID 60108785, compound

https://huagongshe.com/reaction/1005658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 60108780HCID 60108780—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 60108785HCID 6010878577.5%

Reaction Steps

To a solution of 4-(1H-indol-7-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester (100 mg) in EtOH (20 mL) was added 10% Pd/C (20 mg). The reaction was placed on a Parr shaker at 55 psi H2 for 24 h. The reaction was filtered through Celite™ and concentrated to afford 4-(1H-indol-7-yl)-piperidine-1-carboxylic acid tert-butyl ester (22) as a clear oil (78 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787535B2
Source datasetuspto-grants-2004_09
ORD IDord-52d04bef45344eb5a04475b15473f9a6
Source noteuspto-grants-2004_09