反应详情

In ethanol (150 ml) was suspended N-(3-nitrophenethyl)phthalimide obtained in Preparation Example 26. To the mixture was added hydrazine (5.7 ml), followed by heating under reflux for 1 hour. Though the reaction mixture was once completely dissolved, crystals again precipitated. The crystals were filtered off and washed with cooled ethanol. Then, the solvent was evaporated, to give the title compound (5.559 g, 99%) as a yellow oil.

1. customobtained in Preparation Example 26
2. temperatureby heating
3. temperatureunder reflux for 1 hour
4. dissolutionThough the reaction mixture was once completely dissolved
5. customcrystals again precipitated
6. filtrationThe crystals were filtered off
7. washwashed with cooled ethanol
8. customThen, the solvent was evaporated