反应详情

In pyridine (5 ml) was dissolved 1.7 g of N-acetyl-N-(3-aminophenethyl)amine (Preparation Example 29), followed by dropwise addition of ethyl chloroformate (1.4 ml) under ice-cooling. After stirring at room temperature for 1 hour, the mixture was ice-cooled again. Water was added thereto, followed by extracting with ethyl acetate. The extract was washed with brine, dried over anhydrous magnesium sulfate and the solvent was evaporated, to give the title compound (2.358 g, 97%) as a yellow oil.

1. temperaturecooling
2. temperaturecooled again
3. extractionby extracting with ethyl acetate
4. washThe extract was washed with brine
5. dry with materialdried over anhydrous magnesium sulfate
6. customthe solvent was evaporated