Water → HCID 60108820, compound

Participants

Reaction Steps

A mixture of 2-hydrazinothieno[3,2-d]pyrimidin-4-yl 2-thienylmethanone (110 mg, 0.4 mmol) and Et3N (61 μL, 0.44 mmol) in THF (5 mL) was treated with methanesulphonyl chloride (31 μl, 0.4 mmol), stirred at room temperature for 20 min, poured into water (25 mL), extracted with EtOAc (2×5 mL), dried (MgSO4) and concentrated in vacuo. The crude product was purified by chromatography [SiO2: (EtOAc) to give the title compound (92 mg, 65%) as an orange solid.

Provenance & Evidence