Acetic Anhydride → HCID 178475112, compound

HRID 1005738Notes

Reaction equation

HRID 1005738 reaction equation
[OH:1][C:2]1[C:3]([C:8]([NH2:10])=[O:9])=[N:4][CH:5]=[CH:6][N:7]=1.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([NH:10][C:8]([C:3]1[C:2]([OH:1])=[N:7][CH:6]=[CH:5][N:4]=1)=[O:9])(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 178513804HCID 178513804, compound

Product 1

HCID 178475112HCID 178475112, compound

Conditions

Temperature
110 °C

Procedure

In 5 mL of acetic anhydride is suspended 0.5 g of 3-hydroxy-2-pyrazinecarboxamide. The resulting solution is stirred at 110° C. for 1 hour. The deposited crystals are collected by filtration to obtain 0.5 g of N2-acetyl-3-hydroxy-2-pyrazinecarboxamide.

Workup

  1. filtrationThe deposited crystals are collected by filtration

Sources & evidence

ORD record
ord-42ef9231c4cb4ea8add478ab3b885d10
Source dataset
uspto-grants-2004_09
Patent number
US06787544B2

Reaction notes

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