Ammonia → HCID 135585887, compound

HRID 1005750Notes

Reaction equation

HRID 1005750 reaction equation
[O:1]=[C:2]1[C:7]([C:8]([O:10]CC)=O)=[N:6][N:5]=[CH:4][NH:3]1.[NH3:13]>C(O)C>[O:1]=[C:2]1[C:7]([C:8]([NH2:13])=[O:10])=[N:6][N:5]=[CH:4][NH:3]1

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 135585888HCID 135585888, compound

Product 1

HCID 135585887HCID 135585887, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 5 mL of ethanol is dissolved 0.06 g of ethyl 5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxylate. At 10° C., the solution is saturated with ammonia by introducing gaseous ammonia thereinto for 20 minutes. The solution is allowed to stand at ambient temperature for 15 hours, and the resulting crystals are collected by filtration. The crystals thus obtained are washed successively with two 2 mL portions of ethanol and then two 1 mL portion of methanol to obtain 0.03 g of 5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxamide.

Workup

  1. customAt 10° C.
  2. waitto stand at ambient temperature for 15 hours
  3. filtrationthe resulting crystals are collected by filtration
  4. customThe crystals thus obtained
  5. washare washed successively with two 2 mL portions of ethanol

Sources & evidence

ORD record
ord-549e17ef8e3a4d9f88fc8cc18d99b4e1
Source dataset
uspto-grants-2004_09
Patent number
US06787544B2

Reaction notes

Loading…