Phenol → 2-Chloro-4-phenoxypyridine

HRID 1005911Notes

Reaction equation

HRID 1005911 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([N+]([O-])=O)[CH:5]=[CH:4][N:3]=1.[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[O:17]([C:6]1[CH:5]=[CH:4][N:3]=[C:2]([Cl:1])[CH:7]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 7351522-Chloro-4-nitropyridine

Product 1

HCID 117889672-Chloro-4-phenoxypyridineYield 42.2%

Procedure

The title compound (1.2 g) was prepared by the same procedure as the preparation 1 except for using 2-chloro-4-nitropyridine (2.5 g) and phenol (1.3 g).

Sources & evidence

ORD record
ord-8a6af111eb84465b8fa7b23c56a24ad7
Source dataset
uspto-grants-2004_09
Patent number
US06787551B2

Reaction notes

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