4-Fluorobenzaldehyde → HCID 22675140, compound

HRID 1005913Notes

Reaction equation

[CH3:1][N:2]([CH2:16][CH2:17][OH:18])[C:3]1[N:8]=[CH:7][CH:6]=[C:5]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=2)[N:4]=1.F[C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[O:25])=[CH:22][CH:21]=1>>[CH3:1][N:2]([CH2:16][CH2:17][O:18][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[O:25])=[CH:22][CH:21]=1)[C:3]1[N:8]=[CH:7][CH:6]=[C:5]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=2)[N:4]=1

Participants

Reactant 2

HCID 680234-Fluorobenzaldehyde

HCID 22675088HCID 22675088, compound

Product 1

HCID 22675140HCID 22675140, compoundYield 51.3%

Procedure

The title compound (980 mg) was prepared by the same procedure as the preparation 3 except for using 2-[N-methyl-N-(6-(4-anilinyl)pyrimidinyl)amino]ethanol (1.34 g) and 4-fluorobenzaldehyde (1.13 g).

Sources & evidence

ORD record: ord-6f64a764a15c45f1be176b4642497d0c
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06787551B2

Reaction notes

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