4-Fluorobenzaldehyde → HCID 86592980, compound

HRID 1005914Notes

Reaction equation

[CH3:1][N:2]([CH2:16][CH2:17][OH:18])[C:3]1[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=2)=[N:5][CH:6]=[CH:7][CH:8]=1.F[C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[O:25])=[CH:22][CH:21]=1>>[CH3:1][N:2]([CH2:16][CH2:17][O:18][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[O:25])=[CH:22][CH:21]=1)[C:3]1[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=2)=[N:5][CH:6]=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 680234-Fluorobenzaldehyde

HCID 67023984HCID 67023984, compound

Product 1

HCID 86592980HCID 86592980, compoundYield 58.2%

Procedure

The title compound (3.19 g) was prepared by the same procedure as the preparation 3 except for using 2-[N-methyl-N-(2-(4-anilinyl)pyridinyl)amino]ethanol (3.84 g) and 4-fluorobenzaldehyde (3.2 g).

Sources & evidence

ORD record: ord-d7ba42fef4be4f02a98a6c4d2a51d699
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06787551B2

Reaction notes

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