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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1006032Generated: October 31, 2026

HCID 22675560, compound → HCID 22675476, compound

https://huagongshe.com/reaction/1006032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22675560HCID 22675560—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 22675476HCID 22675476104.8%

Reaction Steps

Methyl 4-[2-(2-(2-chloro-2-(phenyl)ethyl)-3-pyridyl)ethyl]benzoate (0.537 g, 1.29 mmol) was dissolved in ethanol (10 ml). The solution was treated with palladium on carbon (10% Pd, 0.1 g) and placed under a hydrogen atmosphere. The reaction was stirred at ambient temperature for 18 hours, then filtered and the solvent evaporated to give methyl 4-[2-(2-(phenethyl)-3-pyridyl)ethyl]benzoate (0.467 g), which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787562B2
Source datasetuspto-grants-2004_09
ORD IDord-9d5bdf75bbcf45e2a55152883f186ba3
Source noteuspto-grants-2004_09