HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acid → 4-[3-(2-Benzylphenyl)propyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acid | HCID 54402614 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-[3-(2-Benzylphenyl)propyl]benzoic acid | HCID 22675538 | — |
Reaction Steps
A solution of 4-[3-(2-benzylphenyl)prop-1-enyl]benzoic acid (6.43 g) in THF (50 ml) containing 10% palladium on carbon (1 g) was stirred under an atmosphere of hydrogen (balloon) for 15 hours. The catalyst was removed by filtration and the residue obtained on removal of the solvent was purified by chromatography on silica, eluting with 5% methanol in dichloromethane, to give 4-[3-(2-benzylphenyl)propyl]benzoic acid, m.p. 135-6° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787562B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-3ae3170213a44ec2a5144b1284de5d83 |
| Source note | uspto-grants-2004_09 |