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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1006041Generated: October 27, 2026

4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acid → 4-[3-(2-Benzylphenyl)propyl]benzoic acid

https://huagongshe.com/reaction/1006041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acidHCID 54402614—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product4-[3-(2-Benzylphenyl)propyl]benzoic acidHCID 22675538—

Reaction Steps

A solution of 4-[3-(2-benzylphenyl)prop-1-enyl]benzoic acid (6.43 g) in THF (50 ml) containing 10% palladium on carbon (1 g) was stirred under an atmosphere of hydrogen (balloon) for 15 hours. The catalyst was removed by filtration and the residue obtained on removal of the solvent was purified by chromatography on silica, eluting with 5% methanol in dichloromethane, to give 4-[3-(2-benzylphenyl)propyl]benzoic acid, m.p. 135-6° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787562B2
Source datasetuspto-grants-2004_09
ORD IDord-3ae3170213a44ec2a5144b1284de5d83
Source noteuspto-grants-2004_09