HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → Florfenicol Flunixin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Propylene Glycol | HCID 1030 | — |
| Reactant | 1,3-Dioxolane-4-methanol | HCID 21618 | — |
| Reactant | Flunixin Meglumine | HCID 39212 | — |
| Reactant | Florfenicol | HCID 114811 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | Florfenicol Flunixin | HCID 86602307 | — |
Reaction Steps
The NMP or dimethylacetamide, citric acid, propylene glycol, and approximately 90% of the PEG 300 or glycerol formal required for each formulation were charged to the compounding vessel and mixed well. The florfenicol and flunixin meglumine were added with mixing until all solids were dissolved. The volume was adjusted with the remaining PEG 300 or glycerol formal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06790867B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-f638f5ccb58744b6a54966745a9c9f47 |
| Source note | uspto-grants-2004_09 |