HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → Methyl 2-amino-5-chlorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 2-Amino-5-chlorobenzoic acid | HCID 12476 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | Methyl 2-amino-5-chlorobenzoate | HCID 78878 | — |
Reaction Steps
To a suspension of 5-chloroanthranilic acid (6.1 g) in AcOEt-MeOH (20 ml+10 ml), a solution of an excess amount of diazomethane in ether (50 ml) was added at 0° C. After termination of reaction, reaction solvent was evaporated to dryness to give the title compound (6.6 g) having the following physical data.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06790866B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-c2b55e883a0d4e5d9fa380fbc2a1d9ff |
| Source note | uspto-grants-2004_09 |