Ethanol → HCID 69752797, compound

HRID 1006682Notes

Reaction equation

HRID 1006682 reaction equation
CC1[CH:7]=[CH:6][CH:5]=[C:4](C)[C:3]=1[CH:9]=[CH:10][C:11]1[C:12]2[N:13]([C:17]([CH3:21])=[C:18]([CH3:20])[N:19]=2)[CH:14]=[CH:15][CH:16]=1.[CH2:22]([OH:24])[CH3:23].[H][H].[CH3:27]O>[Pd]>[CH3:27][C:9]1[CH:3]=[C:4]([O:24][CH2:22][CH3:23])[CH:5]=[C:6]([CH3:7])[C:10]=1[C:11]1[C:12]2[N:13]([C:17]([CH3:21])=[C:18]([CH3:20])[N:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 887MethanolHCID 69750316HCID 69750316, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 69752797HCID 69752797, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

8-(2-(2,6-dimethylphenyl)ethenyl)-2,3-dimethylimidazo[1,2-a]pyridine was solved in methanol (3 ml) and ethanol (2 ml) and Pd/C (10%) (40 mg) was added. The mixture was hydrogenated at room temperature and atmospheric pressure until the uptake of hydrogen ceased. Following filtration through celite, the solvents were evaporated under reduced pressure to give the title compound, (0.069 g, 100%).

Workup

  1. customwas hydrogenated at room temperature
  2. filtrationfiltration through celite
  3. customthe solvents were evaporated under reduced pressure

Sources & evidence

ORD record
ord-4b3e73f8eeda420ab6ebde27fa73b414
Source dataset
uspto-grants-2004_09
Patent number
US06790960B2

Reaction notes

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