Carbon tetrabromide → [(5-bromopentyl)-oxy]-N-butyl-N-methyl acetamide

Participants

Reaction Conditions

Reaction Steps

13 g of tetrabromo-methane and 10.3 g of triphenyl-phosphine were added at −10° C. to a solution of 7.2 g of the product of Step C in 73 ml of methylene chloride. The reaction medium was stirred for one hour at 0° C. and chromatographed on silica (eluant: ethyl acetate—cyclohexane 7-3) to obtain 7.49 g of the desired compound.

Provenance & Evidence