Water → 2-Bromo-N-isopropyl-N-methyl-acetamide

Participants

Reaction Steps

To a solution of 10 cm3 of acetyl bromide in 150 cm3 of ether, cooled to −20° C., one adds a solution of 26 cm3 of methylisopropylamine in 100 cm3 of ether. One leaves the mixture to return to 20° C. and agitates it for 30 minutes at 20° C. One dilutes with water, decants, extracts with ether, dries and separates by distillation. One obtains 13 g of expected product. B.p.=71/72° under 1 mmHg.

Provenance & Evidence