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HRID1006792

反应详情

EQUATION

反应方程式

HRID 1006792 的结构方程式

REACTANTS

反应物

2
结构：[N-]=[N+]=NC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1
HCID11269582

未命名化合物

结构：CCN(C(C)C)C(C)C.O=C(Cl)OCc1ccccc1
HCID86584840

未命名化合物

PRODUCTS

生成物

1
结构：NC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccccc1
HCID69431427

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

(2S,4R)-2-azidomethyl-4-tritylsulfanyl-pyrrolidine and benzyl chloroformate/N-ethyldiisopropylamine in CH2Cl2 (see cabamate synthesis, Method A)—followed by Staudinger reduction gave (2S,4R)-2-aminomethyl-4-tritylsulfanyl-pyrrolidine-1-carboxylic acid benzyl ester as white foam, MS: 509 (MH+).

WORKUP

后处理

  1. customcabamate synthesis, Method A)—followed by Staudinger reduction