HRID1006793

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID137663

2,5-Difluorobenzaldehyde

C7H4F2O

结构：NC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccccc1

HCID69431427

未命名化合物

PRODUCTS

生成物

结构：O=C(OCc1ccccc1)N1C[C@H](S)C[C@H]1CNCc1cc(F)ccc1F

HCID86584841

未命名化合物

PROCEDURE

实验过程

(2S,4R)-2-aminomethyl-4-tritylsulfanyl-pyrrolidine-1-carboxylic acid benzyl ester and 2,5-difluorobenzaldehyde and subsequent cleavage of the trityl protecting group analogously to reductive amination and deprotection gave (2S,4R)-2-[(2,5-difluoro-benzylamino)-methyl]-4-mercapto-pyrrolidine-1-carboxylic acid benzyl ester as colorless oil, MS: 393 (MH+).