HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → HCID 86588303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Erythromycin | HCID 12560 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86588303 | HCID 86588303 | 83% |
Reaction Steps
The compound is prepared starting from an erythromycin solution (2 g, 2.72 mmoles) dissolved in a mixture of chloroform (30 ml)/acetonitrile (20 ml), by adding a 65% nitric acid solution (0.200 ml) in acetonitrile (5 ml), following then the procedure described in Example 5. Erythromycin nitrate as amorphous solid is obtained. Yield 83%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794372B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-427276c7e5544d2d8f80c0060aaf2f06 |
| Source note | uspto-grants-2004_09 |