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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1007078Generated: October 31, 2026

Nitric Acid → HCID 86588303, compound

https://huagongshe.com/reaction/1007078

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
ReactantErythromycinHCID 12560—
SolventChloroformHCID 6212—
SolventAcetonitrileHCID 6342—
ProductHCID 86588303HCID 8658830383%

Reaction Steps

The compound is prepared starting from an erythromycin solution (2 g, 2.72 mmoles) dissolved in a mixture of chloroform (30 ml)/acetonitrile (20 ml), by adding a 65% nitric acid solution (0.200 ml) in acetonitrile (5 ml), following then the procedure described in Example 5. Erythromycin nitrate as amorphous solid is obtained. Yield 83%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06794372B2
Source datasetuspto-grants-2004_09
ORD IDord-427276c7e5544d2d8f80c0060aaf2f06
Source noteuspto-grants-2004_09