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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1007080Generated: October 30, 2026

Nitric Acid → HCID 86588305, compound

https://huagongshe.com/reaction/1007080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
ReactantAmpicillinHCID 6249—
ReactantTetrahydrofuranHCID 8028—
SolventAcetonitrileHCID 6342—
ProductHCID 86588305HCID 8658830555%

Reaction Steps

The compound is prepared startaing from an Ampicillin solution (2 g, 5.72 rmoles) in a mixture formed by acetonitrile (30 ml) and tetrahydrofuran (20 ml), by adding a 65% nitric acid solution (0.450 ml) in acetonitrile (5 ml) and following the procedure reported in Example 5. Ampicillin nitrate as amorphous solid is obtained. Yield 55%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06794372B2
Source datasetuspto-grants-2004_09
ORD IDord-0f959745bcf34a61bb1ec65e48641842
Source noteuspto-grants-2004_09