HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → HCID 86588305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Ampicillin | HCID 6249 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86588305 | HCID 86588305 | 55% |
Reaction Steps
The compound is prepared startaing from an Ampicillin solution (2 g, 5.72 rmoles) in a mixture formed by acetonitrile (30 ml) and tetrahydrofuran (20 ml), by adding a 65% nitric acid solution (0.450 ml) in acetonitrile (5 ml) and following the procedure reported in Example 5. Ampicillin nitrate as amorphous solid is obtained. Yield 55%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794372B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-0f959745bcf34a61bb1ec65e48641842 |
| Source note | uspto-grants-2004_09 |