Pyridine → HCID 10195526, compound

Participants

Reaction Steps

To a stirred suspension of methyl (6-nitro-3,4-dihydro-2H-1,4-benzoxazin-2-yl)acetate 2 (2.52 g, 10 mmol) and anhydrous sodium carbonate (2 g.) in anhydrous DMF (15 mL) and anhydrous pyridine (5 mL), benzoyl chloride (1.5 mL, 12.96 mmol) was added. The resulting suspension was stirred 8 hours at room temperature. The reaction mixture was then diluted with ethyl acetate (100 mL) and washed with water (3×100 mL). After separation the organic phase was dried (Na2SO4) and evaporated to dryness in vacuo to afford the title compound (3.3 g, 93%) as a yellow-orange oil.

Provenance & Evidence