4-Fluoro-2-nitroaniline → HCID 9900796, compound

HRID 1007179Notes

Reaction equation

HRID 1007179 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[F:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[C:14]([N+:19]([O-:21])=[O:20])[CH:13]=1>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:16][C:15]2[CH:17]=[CH:18][C:12]([F:11])=[CH:13][C:14]=2[N+:19]([O-:21])=[O:20])=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 677694-Fluoro-2-nitroanilineHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 9900796HCID 9900796, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 4-fluoro-2-nitroaniline and was obtained as a yellow solid as described in Example 1. 1H NMR (DMSO-d6): 10.97 (s, 1H), 8.94 (d, J=2.7, 1H), 8.36-8.32 (m, 1H), 8.02-7.98 (m, 1H), 7.78-7.75 (m, 1H), 7.73-7.72 (m, 1H), 7.70 (d, J=1.5, 1H).

Workup

  1. customwas obtained as a yellow solid

Sources & evidence

ORD record
ord-06b73f8bdc8f4d8c8d23b5fc9a64596d
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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