4-Methoxy-2-nitroaniline → HCID 22668916, compound

HRID 1007189Notes

Reaction equation

HRID 1007189 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[C:5]([C:12](Cl)=[O:13])=[CH:4][N:3]=1.[CH3:15][O:16][C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[C:19]([N+:24]([O-:26])=[O:25])[CH:18]=1>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[C:5]([C:12]([NH:21][C:20]2[CH:22]=[CH:23][C:17]([O:16][CH3:15])=[CH:18][C:19]=2[N+:24]([O-:26])=[O:25])=[O:13])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 667934-Methoxy-2-nitroanilineHCID 27367082-Chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl chloride

Product 1

HCID 22668916HCID 22668916, compound

Procedure

The title compound was prepared from 2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl chloride and 4-methoxy-2-nitroaniline and was obtained as a light yellow solid as described in Example 1. 1H NMR (CDCl3): 10.52 (s, 1H), 9.04 (s, 1H), 8.68 (d, J=9.3, 1H), 7.76 (d, J=3.0, 1H), 7.35-7.31 (m, 1H), 3.91 (s, 3H).

Workup

  1. customwas obtained as a light yellow solid

Sources & evidence

ORD record
ord-7cedd79c5d274ed8a5157c44c25cd6e5
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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