4,5-Difluoro-2-nitroaniline → HCID 9922830, compound

HRID 1007194Notes

Reaction equation

HRID 1007194 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[F:11][C:12]1[C:18]([F:19])=[CH:17][C:15]([NH2:16])=[C:14]([N+:20]([O-:22])=[O:21])[CH:13]=1>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:16][C:15]2[CH:17]=[C:18]([F:19])[C:12]([F:11])=[CH:13][C:14]=2[N+:20]([O-:22])=[O:21])=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 1571514,5-Difluoro-2-nitroanilineHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 9922830HCID 9922830, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 4,5-difluoro-2-nitroaniline and was obtained as a yellow solid as described in Example 1. 1H NMR (CDCl3): 11.49 (bs, 1H), 9.04-8.97 (m, 2H), 8.25-8.19 (m, 2H), 7.56-7.53 (m, 1H).

Workup

  1. customwas obtained as a yellow solid

Sources & evidence

ORD record
ord-c3e89770ee9e458faa515c01ab9d668f
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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