4-Ethoxy-2-nitroaniline → HCID 9900998, compound

HRID 1007208Notes

Reaction equation

HRID 1007208 reaction equation
[CH3:1][C:2]1[CH:7]=[N:6][C:5]([C:8]([OH:10])=O)=[CH:4][N:3]=1.[CH2:11]([O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[C:16]([N+:21]([O-:23])=[O:22])[CH:15]=1)[CH3:12]>>[CH3:1][C:2]1[N:3]=[CH:4][C:5]([C:8]([NH:18][C:17]2[CH:19]=[CH:20][C:14]([O:13][CH2:11][CH3:12])=[CH:15][C:16]=2[N+:21]([O-:23])=[O:22])=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 692294-Ethoxy-2-nitroanilineHCID 1228315-Methyl-2-pyrazinecarboxylic acid

Product 1

HCID 9900998HCID 9900998, compound

Procedure

The title compound was prepared from 2-methylpyrazine-5-carboxylic acid and 4-ethoxy-2-nitroaniline as a yellow solid as described in Example 15. 1H NMR (CDCl3): 12.82 (s, 1H), 9.36 (s, 1H), 8.90 (d, J=9.6, 1H), 8.56 (d, J=1.0. 1H), 7.74 (d, J=2.7, 1H), 7.32-7.29 (m, 1H), 4.11 (q, J=6.9, 2H), 2.71 (s, 3H), 1.46 (t, J=6.9, 3H).

Sources & evidence

ORD record
ord-8749249c7f9c4bceb379e4727e8b3d78
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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