4-Ethoxy-2-nitroaniline → HCID 22668938, compound

HRID 1007212Notes

Reaction equation

HRID 1007212 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[CH2:11]([O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[C:16]([N+:21]([O-:23])=[O:22])[CH:15]=1)[CH3:12]>>[Br:1][C:2]1[CH:10]=[C:6]([C:7]([NH:18][C:17]2[CH:19]=[CH:20][C:14]([O:13][CH2:11][CH3:12])=[CH:15][C:16]=2[N+:21]([O-:23])=[O:22])=[O:9])[CH:5]=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 692294-Ethoxy-2-nitroanilineHCID 887075-Bromonicotinic acid

Product 1

HCID 22668938HCID 22668938, compound

Procedure

The title compound was prepared from 5-bromonicotinic acid and 4-ethoxy-2-nitroaniline as a yellow solid as described in Example 15. 1H NMR (CDCl3): 11.11 (s, 1H), 9.11 (d, J=2.1, 1H), 8.88 (d, J=1.8, 1H), 8.80 (d, J=9.3, 1H), 8.42 (t, J=2.1, 1H), 7.75 (d, J=2.7, 1H), 7.34-7.30 (m, 1H), 4.12 (q, J=6.9, 2H), 1.47 (t, J=6.9, 3H).

Sources & evidence

ORD record
ord-bdc245b828db424a98240c39988ee0de
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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