4-Ethoxy-2-nitroaniline → HCID 9878675, compound

HRID 1007213Notes

Reaction equation

HRID 1007213 reaction equation
[NH:1]1[CH:5]=[CH:4][C:3]([C:6]([OH:8])=O)=[CH:2]1.[CH2:9]([O:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[C:14]([N+:19]([O-:21])=[O:20])[CH:13]=1)[CH3:10]>>[CH2:9]([O:11][C:12]1[CH:18]=[CH:17][C:15]([NH:16][C:6]([C:3]2[CH:4]=[CH:5][NH:1][CH:2]=2)=[O:8])=[C:14]([N+:19]([O-:21])=[O:20])[CH:13]=1)[CH3:10]

Participants

3

Reactant 2

HCID 692294-Ethoxy-2-nitroanilineHCID 101030Pyrrole-3-carboxylic acid

Product 1

HCID 9878675HCID 9878675, compound

Procedure

The title compound was prepared from pyrrole-3-carboxylic acid and 4-ethoxy-2-nitroaniline as a yellow solid as described in Example 15. 1H NMR (CDCl3): 10.82 (s, 1H), 8.88 (d, J=9.3, 1H), 8.65 (s, 1H), 7.70 (d, J=3.0, 1H), 7.54-7.52 (m, 1H), 7.28-7.24 (m, 1H), 6.87-6.85 (m, 1H), 6.71-6.69 (m, 1H), 4.08 (q, J=6.9, 2H), 1.45 (t, J=6.9, 3H).

Sources & evidence

ORD record
ord-3edebe996ad54838a02ff702700ae1ab
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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