2-Amino-4,5-dimethoxybenzonitrile → HCID 10267884, compound

HRID 1007217Notes

Reaction equation

HRID 1007217 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[NH2:11][C:12]1[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[CH:16][C:13]=1[C:14]#[N:15]>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:11][C:12]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[CH:16][C:13]=2[C:14]#[N:15])=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 7359672-Amino-4,5-dimethoxybenzonitrileHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 10267884HCID 10267884, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 2-amino-4,5-dimethoxybenzonitrile as a white solid as described in Example 1. 1H NMR (CDCl3): 8.97 (d, J=2.7, 1H), 8.18-8.15 (m, 3H), 7.52 (d, J=8.4, 1H), 7.02 (s, 1H), 4.01 (s, 3H), 3.92 (s, 3H).

Sources & evidence

ORD record
ord-75505eab692341518417aef7a18dee10
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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