HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-Amino-1,3-benzodioxol-5-yl)ethan-1-one → N-(6-acetylbenzo[d][1,3]dioxol-5-yl)-6-chloronicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-Amino-1,3-benzodioxol-5-yl)ethan-1-one | HCID 120000 | — |
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Product | N-(6-acetylbenzo[d][1,3]dioxol-5-yl)-6-chloronicotinamide | HCID 22668937 | — |
Reaction Steps
The title compound was prepared from 6-chloronicotinoyl chloride and 2-amino-4,5-methylenedioxyacetophenone as a light grey-yellow solid as described in Example 1. 1H NMR (CDCl3): 9.09-9.08 (m, 1H), 8.55 (s, 1H), 8.30-8.27 (m, 1H), 7.50-7.47 (m, 1H), 7.35 (s, 1H), 6.10 (s, 2H), 2.64 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794397B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-da1a5f409be0466eb2ef2b96eccfe875 |
| Source note | uspto-grants-2004_09 |