5-Amino-2-chloropyridine → HCID 9816824, compound

HRID 1007224Notes

Reaction equation

HRID 1007224 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[NH2:11][C:12]1[CH:13]=[CH:14][C:15]([Cl:18])=[N:16][CH:17]=1>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:11][C:12]2[CH:13]=[CH:14][C:15]([Cl:18])=[N:16][CH:17]=2)=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 793055-Amino-2-chloropyridineHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 9816824HCID 9816824, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 5-amino-2-chloropyridine as a white solid as described in Example 1. 1H NMR (CDCl3): 8.89-8.84 (m, 1H), 8.52 (d, J=2.1, 1H), 8.27-8.23 (m, 1H), 8.21-8.17 (m, 1H), 7.83 (s, 1H), 7.53-7.50 (m, 1H), 7.39 (d, J=8.7, 1H).

Sources & evidence

ORD record
ord-781f9f7deeb94d708d28b46370296c7a
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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