HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-trifluoromethyl-5-thiazolecarbonyl chloride → Methyl 5-{[2-Chloro-4-(trifluoromethyl)-5-thiazolyl]carbonylamino}-2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-trifluoromethyl-5-thiazolecarbonyl chloride | HCID 13282744 | — |
| Reactant | Methyl 5-amino-2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate | HCID 15676771 | — |
| Product | Methyl 5-{[2-Chloro-4-(trifluoromethyl)-5-thiazolyl]carbonylamino}-2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate | HCID 18174413 | — |
Reaction Steps
Methyl 5-amino-2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate (example A1 of U.S. Pat. No. 5,114,465) was reacted with 2-chloro-4-(trifluoromethyl)-5-thiazolecarbonyl chloride according to the procedure in example 1 of U.S. Pat. No. 5,114,465 afforded the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794396B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-fccc69f5d4ff4649bddd31102c59936b |
| Source note | uspto-grants-2004_09 |