Sodium Hydroxide → HCID 22668887, compound

HRID 1007252Notes

Reaction equation

[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[C:16]([CH3:17])=[C:15]([C:18]([F:21])([F:20])[F:19])[N:14]=[CH:13][C:12]=2[C:22]([O:24]C)=[O:23])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[OH-].[Na+]>>[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([S:10][C:11]2[C:16]([CH3:17])=[C:15]([C:18]([F:20])([F:21])[F:19])[N:14]=[CH:13][C:12]=2[C:22]([OH:24])=[O:23])=[CH:8][CH:9]=1)([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 22668804HCID 22668804, compound2×

Product 1

HCID 22668887HCID 22668887, compound

Procedure

Methyl 4-(4-isopropylphenylthio)-5-methyl-6-(trifluoromethyl)-3-pyridinecarboxylate (compound 11) was hydrolyzed with sodium hydroxide to give the product.

Workup

customto give the product

Sources & evidence

ORD record: ord-de1ae1b8fbc34202868700d8dfba2f25
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06794396B2

Reaction notes

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