3-(Trifluoromethyl)benzaldehyde → 4-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-[3-(trifluoromethyl)benzylidene]thiosemicarbazide

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared from a mixture of N1-bicyclo[2.2.1]hept-5-en-2-ylhydrazine-1-carbothioamide (100 mg, 0.56 mmol) and 3-(trifluoromethyl)benzaldehyde (75 μL, 0.56 mmol) similar to Example 3 and isolated as a white solid (15 mg, 8%). 1H NMR (CDCl3): 9.43 (s, 1H), 7.86-7.80(m, 3H), 7.67 (d, J=8.1 Hz, 1H), 7.56 (t, J=7.7 Hz, 1H), 7.45 (d, J=6.6 Hz, 1H), 6.25-6.15 (m, 2H), 4.32-4.28 (m, 1H), 3.08 (s, 1H), 2.99 (s, 1H), 1.96-1.89 (m, 1H), 1.69 (d, J=9.0 Hz, 1H), 1.50 (d, J=9.6 Hz, 1H), 1.48-1.41 (m, 1H).

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