Picolinic acid → HCID 9900588, compound

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A mixture of N1-bicyclo[2.2.1]hept-5-en-2-ylhydrazine-1-carbothioamide (100 mg, 0.545 mmol), picolinic acid (67 mg, 0.545 mmol) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (104 mg) in dichloromethane (5 mL) was stirred at room temperature for 24 h and isolated as a white solid (47 mg, 30%). 1H NMR (CDCl3): 10.57 (s, 1H), 9.20 (s, 1H), 8.63 (d, J=4.2 Hz, 1H), 8.06 (d, J=7.5 Hz, 1H), 7.89-7.83 (m, 1H), 7.51-7.47 (m, 1H), 7.02 (brs, 1H), 6.16-6.06 (m, 2H), 4.11 (s, 1H), 2.96 (s, 1H), 2.83 (s, 1H), 1.84-1.76 (m, 1H), 1.38-1.28 (m, 3H).

Provenance & Evidence