4-Chlorobenzohydrazide → HCID 9880007, compound

HRID 1007276Notes

Reaction equation

HRID 1007276 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]=[C:10]=[O:11].[Cl:12][C:13]1[CH:22]=[CH:21][C:16]([C:17]([NH:19][NH2:20])=[O:18])=[CH:15][CH:14]=1>C(Cl)Cl>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:11])[NH:20][NH:19][C:17](=[O:18])[C:16]1[CH:15]=[CH:14][C:13]([Cl:12])=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 108164-ChlorobenzohydrazideHCID 52075851-isocyanato-2,4-dimethylbenzene

Product 1

HCID 9880007HCID 9880007, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from a mixture 2,4-dimethylphenylisocyanate (50 mg, 34 mmol) and 4-chlorobenzoic acid hydrazide (63 mg, 37 mmol) in methylenedichloride (10 ml). The mixture was stirred at room temperature for 2 h and the resultant precipitate was collected by filtration and isolated as pale white solid (90 mg, 89%). 1H NMR (DMSO-d6): 10.39 (s, 1H), 8.34 (s, 1H), 8.05 (s, 1H), 7.94 (d, J=6.6 Hz, 1H), 7.57 (d, J=6.6 Hz, 1H), 7.44 (d, J=7.5 Hz, 1H), 6.96 (s, 1H), 6.92 (d, J=7.5 Hz, 1H), 2.72 (s, 3H), 2.22 (s, 3H), 2.16 (s, 3H).

Workup

  1. filtrationthe resultant precipitate was collected by filtration

Sources & evidence

ORD record
ord-4e4c7305963141e9a57c93f5de46ea1a
Source dataset
uspto-grants-2004_09
Patent number
US06794400B2

Reaction notes

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