4-Morpholino-3-nitrobenzaldehyde → HCID 85325821, compound

Participants

Reaction Steps

The title compound was prepared from a mixture of N1-bicyclo[2.2.1]hept-5-en-2-ylhydrazine-1-carbothioamide (35 mg, 0.21 mmol) and 4-morpholino-3-nitrobenzaldehyde (68 mg, 0.287 mmol) similar to Example 3 and isolated as a yellow solid (42 mg, 52%). 1H NMR (CDCl3): 9.91 (s, 1H), 7.90 (d, J=2.1 Hz, 1H), 7.22 (s, 1H), 7.58 (dd, J=8.8, 2.4 Hz, 1H), 7.18 (d, J=2.4 Hz, 1H), 7.01 (d, J=8.8 Hz, 1H), 6.10 (ddd, J=8.1, 5.1, 2.7 Hz, 2H), 4.27 (t, J=8.7 Hz, 1H), 3.75-3.72 (m, 4H), 3.02-2.99 (m, 4H), 2.93 (s, 1H), 2.85 (s, 1H), 1.82 (ddd, J=7.6, 7.0, 2.4 Hz, 1H), 1.57 (m, 1H), 1.39-1.28 (m, 2H).

Provenance & Evidence