Aluminium lithium hydride → HCID 178520956, compound

Participants

Reaction Steps

Under argon stream, a suspension of 2.96 g of lithium aluminum hydride in 100 mL of anhydrous tetrahydrofuran was treated dropwise with a solution of 3.9 g of trans-1,4-cyclohexanedicarboxylic acid dimethyl ester in anhydrous tetrahydrofuran at −20° C., and stirred for 2.5 hours. The reaction solution was combined with ice water to complete the reaction, and the insolubles were filtered off through Celite. After drying over magnesium sulfate, the residue was concentrated to obtain 2.80 g of the desirable compound.

Provenance & Evidence