Azetidin-1-yl(5-bromothiophen-2-yl)methanone → [4-[5-(Azetidine-1-carbonyl)thiophen-2-yl]phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

HRID 100730Notes

Reaction equation

HRID 100730 reaction equation
[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[N:9]([C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18]([B:21]4[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]4)[cH:19][cH:20]3)[CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1.[N:30]1([C:34](=[O:35])[c:36]2[s:37][c:38]([Br:41])[cH:39][cH:40]2)[CH2:31][CH2:32][CH2:33]1>>[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[N:9]([C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18](-[c:38]4[s:37][c:36]([C:34]([N:30]5[CH2:31][CH2:32][CH2:33]5)=[O:35])[cH:40][cH:39]4)[cH:19][cH:20]3)[CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 59264666Azetidin-1-yl(5-bromothiophen-2-yl)methanoneHCID 178426156HCID 178426156, compound

Product 1

HCID 11697853[4-[5-(Azetidine-1-carbonyl)thiophen-2-yl]phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

Sources & evidence

ORD record
ord-8513bd3a54bf4e62a1e7818e5347d8a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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