tert-Butyldimethylsilyl chloride → HCID 11387060, compound

HRID 1007355Notes

Reaction equation

HRID 1007355 reaction equation
[Br:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17]C)=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19]C)[CH:3]=1.[C:21]([Si:25](Cl)([CH3:27])[CH3:26])([CH3:24])([CH3:23])[CH3:22]>>[Br:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:12]=[CH:13][C:14]([O:17][Si:25]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:27])[CH3:26])=[CH:15][CH:16]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19][Si:25]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:27])[CH3:26])[CH:3]=1

Participants

3

Reactant 2

HCID 28928tert-Butyldimethylsilyl chlorideHCID 121489697-Bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole

Product 1

HCID 11387060HCID 11387060, compound

Procedure

The title compound was prepared in substantially the same manner as described in Example 24, Route a, Step a, from 7-bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole, and tert-butyl(chloro)dimethylsilane. The desired product was obtained as a white solid, m.p. 90-91° C.; MS m/e 534 (M+H)+.

Workup

  1. customThe title compound was prepared in substantially the same manner

Sources & evidence

ORD record
ord-e9acb65f17ec4892a160593ba1baa73f
Source dataset
uspto-grants-2004_09
Patent number
US06794403B2

Reaction notes

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