Acetic Anhydride → 1-Acetyl-3-(1-ethoxy-1-phenyl-methylidene)-6-phenyl-2-indolinone
Reaction equation
[C:1]1([C:7]2[CH:15]=[C:14]3[C:10]([CH2:11][C:12](=[O:16])[NH:13]3)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]([O:26][CH2:27][CH3:28])(OCC)(OCC)[CH2:18][CH3:19].C(O[C:33](=[O:35])[CH3:34])(=O)C>>[C:33]([N:13]1[C:14]2[C:10](=[CH:9][CH:8]=[C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH:15]=2)[C:11](=[C:17]([O:26][CH2:27][CH3:28])[C:18]2[CH:19]=[CH:3][CH:2]=[CH:1][CH:6]=2)[C:12]1=[O:16])(=[O:35])[CH3:34]Participants
4
Procedure
Prepared from 6-phenyl-2-indolinone, triethyl orthopropionate and acetic anhydride
Sources & evidence
- ORD record
- ord-801968ab104f4f35bc2cddff2a8e6b3b
- Source dataset
- uspto-grants-2004_09
- Patent number
- US06794395B1
Reaction notes
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