Acetic Anhydride → 1-Acetyl-3-(1-ethoxy-1-phenyl-methylidene)-6-(2-tolyl)-2-indolinone
Reaction equation
[C:1]1([CH3:17])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:15]=[C:14]2[C:10]([CH2:11][C:12](=[O:16])[NH:13]2)=[CH:9][CH:8]=1.[C:18]([O:27][CH2:28][CH3:29])(OCC)(OCC)[CH2:19][CH3:20].C(O[C:34](=[O:36])[CH3:35])(=O)C>>[C:34]([N:13]1[C:14]2[C:10](=[CH:9][CH:8]=[C:7]([C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=3[CH3:17])[CH:15]=2)[C:11](=[C:18]([O:27][CH2:28][CH3:29])[C:19]2[CH:20]=[CH:3][CH:2]=[CH:1][CH:6]=2)[C:12]1=[O:16])(=[O:36])[CH3:35]Participants
4
Procedure
Prepared from 6-(2-tolyl)-2-indolinone, triethyl orthopropionate and acetic anhydride
Sources & evidence
- ORD record
- ord-72204fe13b0f46bea92a2f4c3e378823
- Source dataset
- uspto-grants-2004_09
- Patent number
- US06794395B1
Reaction notes
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