N-(4-Aminophenyl)-2-(dimethylamino)-N-methylacetamide → N-[4-[[(Z)-(5,6-dimethoxy-2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]phenyl]-2-(dimethylamino)-N-methylacetamide

HRID 1007405Notes

Reaction equation

HRID 1007405 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][C:9]([O:15][CH3:16])=[C:10]([O:13][CH3:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH3:28][N:29]([CH2:31][C:32]([N:34]([CH3:42])[C:35]1[CH:40]=[CH:39][C:38]([NH2:41])=[CH:37][CH:36]=1)=[O:33])[CH3:30]>>[CH3:30][N:29]([CH2:31][C:32]([N:34]([C:35]1[CH:36]=[CH:37][C:38]([NH:41]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][C:9]([O:15][CH3:16])=[C:10]([O:13][CH3:14])[CH:11]=3)/[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[CH:39][CH:40]=1)[CH3:42])=[O:33])[CH3:28]

Participants

3

Reactant 2

HCID 22569697N-(4-Aminophenyl)-2-(dimethylamino)-N-methylacetamideHCID 695643221-Acetyl-3-(1-ethoxy-1-phenylmethylidene)-5,6-dimethoxy-2-indolinone

Product 1

HCID 178486547N-[4-[[(Z)-(5,6-dimethoxy-2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]phenyl]-2-(dimethylamino)-N-methylacetamide

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5,6-dimethoxy-2-indolinone and N-(dimethylaminomethylcarbonyl)-N-methyl-p-phenylenediamine

Sources & evidence

ORD record
ord-fdeea66a5a0e4de78da11ea6998a6922
Source dataset
uspto-grants-2004_09
Patent number
US06794395B1

Reaction notes

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